Xiaoyu Guo
School of Pharmaceutical Sciences,
Peking University, Associated Professor
Research Areas
Pharmacognosy
Metabolism of Traditional Chineses Medicine
Education & Positions
Shenyang Pharmaceutical University, Ph.D., 2001-2005
School of Pharmaceutical Sciences, Peking University, Lecturer, 2006-2013
School of Pharmaceutical Sciences, Peking University, Associated Professor, 2013-present
Faculty Accolades
Peking University Youth Post Expert
Peking University Health Science Center Youth Post Expert
Peking University Health Science Center Excellent Youth Scholar Awards
Excellent Teaching Prize of Peking University Health Science Center
Research Interests
Traditional Chinese medicine (TCM) has multi-component and multi-target characteristics. Our research mainly focuses on the metabolism, pharmacokinetics and metabolomics of TCM. Based on the combination of chemical, analytical chemical and biological tools and techniques, we want to elucidate the dynamic process of exogenous and endogenous substances in vivo. Our research provides effective strategy for revealing the pharmacodynamics substance base and mechanism of TCM.
Grants and fundings
National Natural Science Foundation of China, 30701078, 2008.1-2010.12
Beijing Natural Science Foundation, 7123221, 2012.1-2013.6
Natural Science Foundation of China, 81573684, 2016.1-2019.12
Principal Investigator
Publications
1. Yuqing Meng1, Zhiyong Du1, Yan Li, Lichao Wang, Peng Gao, Xiaoyan Gao, Chun Li, Mingbo Zhao, Yong Jiang, Pengfei Tu andXiaoyu Guo*. Integration of metabolomics with pharmacodynamics to elucidate the anti-myocardial ischemia effects of combination of notoginseng total saponins and safflower total flavonoids. Frontiers in Pharmacology, 2018, 9, 667.
2. Xiaoli Ma1, Xiaoyu Guo1, Yuelin Song, Lirui Qiao, Wenguang Wang, Mingbo Zhao, Pengfei Tu, Yong Jiang*. An Integrated Strategy for Global Qualitative and Quantitative Profling of Traditional Chinese Medicine Formulas: Baoyuan Decoction as a Case. Scientific Reports, 2016, 6, Article number: 38379.
3. Xiaoyu Guo, Dan Liu, Min Ye, Jian Han, Sa Deng, Xiaochi Ma, Yanyan Zhao, Baojing Zhang, Xuan Shen, Qingming Che*. Structural characterization of minor metabolites and pharmacokinetics of ganoderic acid C2 in rat plasma by HPLC coupled with electrospray ionization tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 2013, 75, 64-73.
